The boll weevil Anthonomus grandis Boheman, is one of the major pests of cotton in Brazil. There have been many attempts to locate sources of resistance to this insect in many places where it occurs. Several researchers have mentioned primitive Gossypium hirsutum L. that have given significant reduction in oviposition punctures under laboratory tests. Some lines have imposed significant reduction in boll weevil populations under field conditions. Some progenies derived from crosses between these race stocks and cultivars Stoneville 213, PNH3 and CNPA Precoce 2, exhibited significant levels of resistance to boll weevil while maintaining good fiber and agronomic characteristics.